Dr. Tariq Mahmood
Comparative efficacy of two anti-aging products containing Retinyl palmitate in healthy human volunteers
Dr. Tariq Mahmood is an Assistant Professor and Head of Department – Pharmaceutics at University of Central Punjab, Lahore – Pakistan. He received his Ph.D. from the Islamia University of Bahawalpur in 2013. His research interests include aging, trans-dermal drugs, cosmetics (safety, efficacy and quality control), cosmeceuticals, multiple emulsions, oleogels and reactive oxygen species. Dr. Tariq has published over 50 research articles on cosmetics and cosmeceuticals sciences. He is currently reviewer / editorial board member of more than ten international journals including but not limited to Cosmetics, Health Sciences, Natural Products and Clinical research Journals. In 2012, Dr. Tariq was nominated for the 1st Lush Prize 2012 award held in UK. Based on his Ph.D. research he was nominated for Lush Prize. In “Young Researcher Award” category, Dr. Tariq was the only one short listed from all over the Asia.
In this comparative study, efficacy of two over the counter available anti-aging products has been evaluated using the techniques involving analysis of skin images.
The objective of this research was to evaluate the efficacy of formulations containing Retinyl Palmitate intended to reduce facial wrinkles in a single blind, split-face study using a high resolution UVA video camera Visioscan ® VC98. The effects produced by creams on skin wrinkles were measured by non-invasive UVA video camera Visioscan ® VC98 and surface evaluation parameters of the living skin (SEw) evaluated by the software for surface evaluation of living skin (SELS). Total 11 healthy male volunteers, after consent, were selected to participate in the single blind split-face design study with the mean age of 25.5 years. Every volunteer applied one type of cream on the left side and other type of cream on the right side of the face, every night before sleeping as directed according to the study design for 60 days. Measurements of the parameter (SEw) taken at 0, 1st, 7th, 15th, 30th and 60th day of study period using non invasive UVA video camera Visioscan ® VC98. Comparison of the results after 60 days use of both the creams showed significant improvement in SEw parameter of the skin. Statistical evaluation signifies that L’OREAL REVITALIFT has better efficacy to improve the SEw parameter of the skin than PONDS AGE MIRACLE.
It was concluded that constituents in both creams have potentially influenced skin surface parameter, thus indicating that, these creams as a better option to lessen the affects of aging on facial skin.