Sanjay Kapur, MD
- Gut Inflammation and Chronic Diseases: How to Cool the Fire Inside your Gut
- Testosteronel Replacement Therapy in Men
- Stress and Cardiovasular Disease: Is Cortisol the Key?
Dr. Sanjay Kapur is the CEO at AYUMETRIX, a Research and Diagnostic Organization that offers specialized high complexity functional laboratory consulting services for platform technology firms and diagnostic companies. He is an internationally known and recognized anti-aging expert, with dozens of peer-reviewed publications and abstracts, as well as numerous invited presentations. He is a highly-sought speaker on health and wellness at international medical conferences. Dr. Kapur’s strong desire and passion to educate physicians all around the world motivated him to found the Society for Regenerative, Aesthetics and Anti-Aging Society of India. He also serves on Editorial and Scientific Boards of several scientific journals and international anti-aging societies.
Gut Inflammation and Chronic Diseases: How to Cool the Fire Inside your Gut
One of the most insidious consequences of hormonal imbalances, and insulin resistance in particular, is inflammation, which is now thought to be at the root of all chronic illness we experience — from heart disease, obesity and diabetes to dementia, depression, cancer and even autism.
Inflammation and immune balance are yet another one of the body’s core systems we must address to prevent disease and power our vitality. We may feel healthy, but if this inflammation is raging inside of us, we’re in trouble. The real concern is not our acute inflammatory response to injury or infection, but the chronic smoldering inflammation that slowly destroys our organs, compromises our ability for optimal functioning and leads to rapid aging.
As the prevalence of obesity and associated diseases continues to rise and concerns for the spiraling economic and social costs also escalate, innovative management strategies beyond primary prevention and traditional lifestyle interventions are urgently needed. Several key inflammatory markers have been consistently associated with both obesity and related chronic diseases, which suggests that a persistent, low-grade, inflammatory response is a potentially modifiable risk factor. This presentation discusses supporting perturbation of the intestinal microbiota and changes in intestinal permeability as potential triggers of inflammation in chronic disorders. Further characterization of the mechanisms underpinning the triggers of such inflammatory responses in high risk individuals could offer unique opportunities for intervention strategies to help ameliorate the risk of chronic diseases.
Testosterone Replacement Therapy in Men
Low testosterone levels are prevalent in aging men – the Hypogonadism in Men (HIM) study found that almost 39% of men aged 45 and older, who went to their primary care doctor’s office for any reason, had low testosterone levels. The contribution of low testosterone levels to the development of diabetes, is a critical aspect of men’s health that could have a major impact on preventive medicine.
The decline in testosterone levels as men age has been compared to the hormonal impact of menopause in women. Referred to as “andropause”, its impact on the development of cardiovascular disease is as important as that of menopause, but many men are unaware that hormone replacement therapy is not just an option for their female counterparts. This presentation outlines the serious consequences of low testosterone levels for men’s long-term health and cardiovascular wellness and identifies appropriate screening strategies that can direct lifestyle changes and possibly testosterone supplementation to prevent risk of developing diabetes.
Stress and Cardiovascular Disease: Is Cortisol the Key?
High cortisol levels can be seen as a result of some rare forms of cancer affecting the hypothalamic-pituitary axis, but most commonly they are a result of persistent emotional or physical stress. Whatever the cause, high cortisol induces sweeping changes in the body’s chemistry that, under normal conditions, would prepare the body for “fight or flight”. When stress conditions persist, these changes are sustained and start to affect long-term health. Reproductive and immune functions are suppressed, bone density decreases, and abdominal fat increases. Many of these changes lead ultimately to an increased risk of diabetes and cardiovascular disease. The problem of high cortisol levels is now a significant health problem in societies characterized by stressful lifestyles, and we could see a big impact on health as a result of the current economic crisis in many countries around the world. Treatment of stress can be an important part of reducing diabetes and cardiovascular disease risk.
Emotional and physical stress can lead to chronically high cortisol levels, which have a huge impact on overall health. Cortisol is central to many biochemical processes and is not supposed to remain high for long periods. This presentation outlines what happens when this hormone is out of balance, and how it creates ripple effects that ultimately impact cardiovascular health.