Asst. Prof. Pansak Sugkraroek MD. FRCOG (T)
Hormonal optimization through quality sleep
Medical School: M.D., Faculty of Medicine, Ramathibodi Hospital, Mahidol University,Thailand, 1974
Board Certifications: Diploma of The Thai Board of Obstetrics & Gynecology, 1981
Fellowships: Reproductive Biology, Loeb Medical Research Institute, Ottawa Civic Hospital, University of Ottawa, 1988-1989
Academic Rank: Assistant Professor, Mahidol University, Thailand
Special Clinical Interests: Infertility, Menopause, Anti-aging Medicine
Hormonal Optimization through quality sleep
Sleep is a major modulator of endocrine function,particularly of pituitary dependent hormonal release. Growth hormone a major anti-aging hormone secretion is stimulate during sleep and in human 60-70 per cent of growth hormone occur during early sleep in association with deep slow (SW) wave. Whether disorganized SW wave contribute to decrease GH secretion in normal aging men is not known but improvement of sleep quality through melatonin induced circadian rhythm is one of the method used in combating hormones imbalance.
Insomnia and decrease sleep quality are widely report among middle age men and women and several large cross sectional community based survey found higher rate of self-reported of poor sleep quality that may attribute to decrease in testosterone and estrogen level.
Estrogen and testosterone supplement had been used for improve sleep quality in middle age men and women with different results. Decrease level of DHEA-S also found in people with problem of insomnia and supplement with DHEA to healthy level make sleep quality better.
Melatonin a novel sleep-promoting hormone may have dual effect on sleep which are acute sleep promotion that typically occur within one hour of administration and ability to alter the phase of underlying circadian rhythm after a repeated treatment which enhance a physiologic hormones production.