Nattavut Wongdeethai, M.D., M.Sc.
- Growth Factors in Platelet Rich Plasma
Growth Factors in Platelet Rich Plasma
Nattavut Wongdeethai M.D., M.Sc., Tappitak Thammuang B.Sc., Jettana Rongdaj B.Sc., Yupa Pengthumand B.Sc., and Patana Teng-umnuay M.D., Ph.D.
Platelets rich plasma (PRP) is claimed to contain high levels of numerous growth factors that can provide clinical benefits. Platelet derived growth factors can promote tissue regeneration and contributes an important part for tissue repair. Currently, PRP injection has been used for various clinical applications such as orthopedics, ophthalmology, and aesthetic medicine due to its great regenerative potential. Our study aim is to compare the amounts of growth factors and inflammatory cytokines from platelet rich plasma obtained from non-smoking and smoking subjects. The results showed that growth factors in PRP in individuals varied from ages and smoking condition. The levels of HGF and FGF2 and inflammatory cytokines IFN-γ and IL-10 are higher in smoking subjects. Our finding suggests that the concentration of PRP derived growth factors could be different among people depend on life styles. A further study is needed to give us better understanding the effects of smoking on PRP derived growth factors in individuals.