Asst. Prof. Mart Maiprasert, M.D.
- Intermittent Fasting for Weight Loss
M.D. 1st Class Honors (Faculty of Medicine, Chulalongkorn University) 1994
Family Medicine 2000
American Board of Anti-Aging and Regenerative Medicine: ABAARM (A4M-USA) 2007
Fellowship in Anti-Aging and Regenerative Medicine: FAARM (A4M-USA) 2010
Fellowship in Aesthetic Medicine (USA) 2012
Fellowship in Cosmetic Surgery (KCCS) 2015
Dr. Mart Maiprasert is an accomplished aesthetic specialist with more than 10 years’ experience. His success has come from the application of anti-aging science into his work in the field of aesthetics medicine and cosmetic surgery. Currently, Dr. Maiprasert owns a private practice at S-Mart Clinic, Bangkok, Thailand and also serves as the Program Director of Master’s Degree of Science in Anti-Aging and Regenerative Medicine at Dhurakit Pundit University.
Diet control is one of successful methods for weight loss. One type of diet control is fasting that is one of most ancient and widespread healing traditions in the world. There are 2 main type of fasting; 1. Intermittent fasting (I.F.) and 2. Prolonged or Periodic fasting (P.F). Examples of Intermittent fasting are Alternate Day Total Fasting (ADTF), Alternate Day Partial fasting (ADPF) and Time Restricted Feeding (TRF).
ADTF means to eat no caloric food or drinks on fasting days, alternate with ad libitum eating days. While ADPF means to consume 25% of energy needs 2 days per week, ad libitum eating on non-fasting days. And TRF means Ad libitum eating within specified time frame such as eating only within a 7- or 8-hour period of time during the day (resulting in 13–16 hour fasting).
Prolonged Fasting means fasting more than 3 days, this will stress body more and produces more profound results (stimulating protectionist and rejuvenation modes). One example of PF that is very popular nowadays and has a lot of evidenced-based beneficial outcomes is Fasting Mimicking Diet (FMD). It is developed by Dr. Valter Longo, University of Southern California Longevity Institute.
IF and FMD are proved to have benefit for losing weight in obesity with preservation of lean mass, improved insulin sensitivity and increased PGC1 alpha that are benefit of diabetic patients, stimulated GH, IGF1 and regulated other hormone homeostasis, improved cardiovascular stress adaptation and heart rate variability, improved blood pressure, decreased CRP and inflammation, improved neuronal resistance to injury, decreased neurodegeneration, stimulated BDNF(Brain Derived Neurotrophic Factor), promoted hippocampal neurogenesis, improved cognitive performance, improved immunity and decreased autoimmune conditions, preserved bone density, promoted stem cells and regenerative markers and also protected cancer, too. IF and FMD are also methods to boost autophagy; programmed cell death that has advantages in cancer, D.M., neurodegenerative disease, fatty liver and infectious disease etc.
IF and FMD seem to have benefits as the same as caloric restriction but possible downsides of IF such as rebound hunger, effects on stress hormone or ability for more intense exercise are not fully explored. And FMD may improve outcome such as autophagy more than other methods and seems to have more compliance because of fewer fasting days per month. So, it may be easier for some people to do on an ongoing basis.