David Bearman, M.D.
- Cannabis, Cannabinoids and the Endocannabinoid System
- Benefits of Cannabis in Health and Diseases
One of the most clinically knowledgeable physicians in the U.S. in the field of medicinal marijuana. He has spent 40 years working in substance and drug abuse treatment and prevention programs. Dr. Bearman was a pioneer in the free and community clinic movement. His career includes public health, administrative medicine, provision of primary care, pain management and cannabinology.
His almost 40-year professional experience in the drug abuse treatment and prevention field includes being the Co-Director of the Haight-Ashbury Drug Treatment Program, being a member of Governor Reagan’s Inter Agency Task Force on Drug Abuse, a member of both the Santa Barbara and the San Diego County Drug Abuse Technical Advisor Committees, and a consultant to Hoffman-LaRoche, Santa Barbara County Schools and the National PTA. He has been recognized by the Santa Barbara Medical Society with the Humanitarian Recognition Award.
Dr. Bearman is also the author of Drugs Are NOT the Devil’s Tools: How Discrimination and Greed Created a Dysfunctional Drug Policy and How It Can Be Fixed in 2 volumes.
CANNABIS, CANNABINOIDS AND THE ENDOCANNABINOID SYSTEM
Botanical historians tell us that Hemp (Cannabis) has existed on the planet for over 35 million years. It is one of the oldest cultivated agricultural plants, having been farmed for at least 10,000 years. Hemp has more than 25,000 industrial uses. Cannabis has been used for over 4,000 years as a medicine and longer as a spiritual aid and as social lubricant.
The Endocannabinoid System (ECS), is arguably the largest neurotransmitters in the human body. The ECS was characterized by researchers in the late 1980’s. It consists of at least two endocannabinoid neurotransmitters, anandamide and 2 AG, two transmitter receptors, CB1 located largely in the brain, and CB2 located primarily in the immune system and two enzymes FAAH and MAGL. Retrograde inhibition and the role of dopamine in that process will be covered.
The cannabis plant, like all plants, is complicated. It has 512 molecules, 113 which are cannabinoids (21 carbon molecules which can block or stimulate CB1, and/or CB2 receptors). Many cannabinoids have therapeutic effects. In addition to cannabinoids there are more than 200 terpenes in the cannabis plant. Terpenes are what give cannabis plants their distinctive odor. Many Terpenes also have therapeutic value. The combined therapeutic effect of the medicinally active cannabinoid and terpenes was postulated by Raphael Mechoulam, PhD. as the entourage effect.
The presentation will provide a foundation for a better understanding of how and why cannabis has been beneficial for treating a wide range of symptoms and medical conditions.
BENEFITS OF CANNABIS IN HEALTH AND DISEASE
The presentation covers how endocannabinoids and phytocannabinoids interact with the body’s own endocannabinoid system to provide therapeutic relief for many conditions. I will address the beneficial effects of some of the cannabinoids and terpenes in the plant. The presentation will cover some specific dosage suggestions. It will include discussion of the entourage effect, (the combined therapeutic effect of all the medically useful constituents of the plant).
The role of retrograde inhibition in treating migraines, seizure disorder, ADD, and Crohm’s disease will be addressed. This mechanism for modulation of the speed of neurotransmission helps to treat anxiety, panic attacks, impulse control, and anger management issues and PTSD.
Cannabis is a also nutracuelicated and a vegetable whose regular use can help maintain good health. It is an anti-oxidant and an anti-inflammatory. It is helpful for vascular health and is neuroproductive. The anti-proliferative effects of cannabis and the mechanisms of action for cannabis anti poetic (anticancer) effect will be covered.
The safety and side effects of this amazing plant that has been used as a medicine for over 4,000 years will also be included in the presentation.